Heterosubtypic immune pressure accelerates emergence of influenza A virus escape phenotypes in mice

Rapid antigenic evolution of the influenza A virus surface antigen hemagglutinin undermines protection conferred by seasonal vaccines. Protective correlates targeted by universal vaccines such as cytotoxic T cells or HA stem directed broadly neutralizing antibodies have been shown to select for immu...

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Detalles Bibliográficos
Autores principales: Chu, Julie TS, Gu, Haogao, Sun, Wanying, Fan, Rebecca LY, Nicholls, John M, Valkenburg, Sophie A, Poon, Leo LM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10194115/
https://www.ncbi.nlm.nih.gov/pubmed/36302472
http://dx.doi.org/10.1016/j.virusres.2022.198991

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10194115/
https://www.ncbi.nlm.nih.gov/pubmed/36302472
http://dx.doi.org/10.1016/j.virusres.2022.198991

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