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Only fourteen 3′-end poly(A)s sufficient for rescuing Senecavirus A from its cDNA clone, but inadequate to meet requirement of viral replication

Senecavirus A (SVA) belongs to the genus Senecavirus in the family Picornaviridae. Its genome is a positive-sense, single-strand RNA that has 5′ and 3′ untranslated regions. There is a poly(A) tail at the 3′ end of viral genome. Although the number of poly(A)s is variable, the length of poly(A) tail...

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Detalles Bibliográficos
Autores principales: Zhao, Di, Li, Yan, Li, Ziwei, Zhu, Lijie, Sang, Yuxuan, Zhang, Hui, Zhang, Feng, Ni, Bo, Liu, Fuxiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10194250/
https://www.ncbi.nlm.nih.gov/pubmed/36841440
http://dx.doi.org/10.1016/j.virusres.2023.199076