Construction of an IL12 and CXCL11 armed oncolytic herpes simplex virus using the CRISPR/Cas9 system for colon cancer treatment

Oncolytic viruses are an emerging cancer treatment modality with promising results in clinical trials. The new generation of oncolytic viruses are genetically modified to enhance virus selectivity for tumor cells and allow local expression of therapeutic genes in tumors. The traditional technique fo...

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Detalles Bibliográficos
Autores principales: Zhang, Nianchao, Li, Jie, Yu, Jingxuan, Wan, Yajuan, Zhang, Cuizhu, Zhang, Hongkai, Cao, Youjia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10194376/
https://www.ncbi.nlm.nih.gov/pubmed/36283533
http://dx.doi.org/10.1016/j.virusres.2022.198979

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10194376/
https://www.ncbi.nlm.nih.gov/pubmed/36283533
http://dx.doi.org/10.1016/j.virusres.2022.198979

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