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A novel method to estimate the absorption rate constant for two-compartment model fitted drugs without intravenous pharmacokinetic data
The in vivo performances of most drugs after extravascular administration are fitted well with the two-compartment pharmacokinetic (PK) model, but the estimation of absorption rate constant (k(a)) for these drugs becomes difficult during unavailability of intravenous PK data. Herein, we developed a...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10194656/ https://www.ncbi.nlm.nih.gov/pubmed/37214472 http://dx.doi.org/10.3389/fphar.2023.1087913 |