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Lymphatic contractile dysfunction in mouse models of Cantú Syndrome with K(ATP) channel gain-of-function
Cantú Syndrome (CS) is an autosomal dominant disorder caused by gain-of-function (GoF) mutations in the Kir6.1 and SUR2 subunits of K(ATP) channels. K(ATP) overactivity results in a chronic reduction in arterial tone and hypotension, leading to other systemic cardiovascular complications. However, t...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10194823/ https://www.ncbi.nlm.nih.gov/pubmed/37214333 http://dx.doi.org/10.1093/function/zqad017 |