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Single Nucleus Sequencing of Human Colon Myenteric Plexus–Associated Visceral Smooth Muscle Cells, Platelet Derived Growth Factor Receptor Alpha Cells, and Interstitial Cells of Cajal

BACKGROUND AND AIMS: Smooth muscle cells (SMCs), interstitial cells of Cajal (ICCs), and platelet-derived growth factor receptor alpha (PDGFRα+) cells (PαCs) form a functional syncytium in the bowel known as the “SIP syncytium.” The SIP syncytium works in concert with the enteric nervous system (ENS...

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Detalles Bibliográficos
Autores principales: Schneider, Sabine, Hashmi, Sohaib K., Thrasher, A. Josephine, Kothakapa, Deepika R., Wright, Christina M., Heuckeroth, Robert O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10194832/
https://www.ncbi.nlm.nih.gov/pubmed/37206377
http://dx.doi.org/10.1016/j.gastha.2022.12.004