HER2 inhibition increases non-muscle myosin IIA to promote tumorigenesis in HER2+ breast cancers

HER2 is over-expressed in around 15% to 20% of breast cancers. HER3 plays a critical role in HER2 mediated tumorigenesis. Increased HER3 transcription and protein levels occur upon inhibition of HER2. We aimed to identify proteins that bound to HER3 upon inhibition of the HER family with the pan-HER...

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Detalles Bibliográficos
Autores principales: Alanazi, Samar M., Feroz, Wasim, Mishra, Rosalin, Kilroy, Mary Kate, Patel, Hima, Yuan, Long, Storr, Sarah J., Garrett, Joan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10194889/
https://www.ncbi.nlm.nih.gov/pubmed/37200287
http://dx.doi.org/10.1371/journal.pone.0285251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10194889/
https://www.ncbi.nlm.nih.gov/pubmed/37200287
http://dx.doi.org/10.1371/journal.pone.0285251

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