Development of a cell-free screening assay for the identification of direct PERK activators

The activation of the unfolded protein response, particularly via the PERK pathway, has been suggested as a promising therapeutic approach in tauopathies, a group of neurodegenerative disorders characterized by the abnormal phosphorylation and aggregation of tau protein. So far, a shortage of availa...

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Detalles Bibliográficos
Autores principales: Costa, Márcia F. D., Höglinger, Günter U., Rösler, Thomas W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10194977/
https://www.ncbi.nlm.nih.gov/pubmed/37200357
http://dx.doi.org/10.1371/journal.pone.0283943

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10194977/
https://www.ncbi.nlm.nih.gov/pubmed/37200357
http://dx.doi.org/10.1371/journal.pone.0283943

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