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Development of a neonatal Göttingen Minipig model for dose precision in perinatal asphyxia: technical opportunities, challenges, and potential further steps

Animal models provide useful information on mechanisms in human disease conditions, but also on exploring (patho)physiological factors affecting pharmacokinetics, safety, and efficacy of drugs in development. Also, in pediatric patients, nonclinical data can be critical for better understanding the...

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Detalles Bibliográficos
Autores principales: Stroe, Marina-Stefania, Van Bockstal, Lieselotte, Valenzuela, Allan, Ayuso, Miriam, Leys, Karen, Annaert, Pieter, Carpentier, Sebastien, Smits, Anne, Allegaert, Karel, Zeltner, Adrian, Mulder, Antonius, Van Ginneken, Chris, Van Cruchten, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10195037/
https://www.ncbi.nlm.nih.gov/pubmed/37215599
http://dx.doi.org/10.3389/fped.2023.1163100