Cannabidiol sensitizes TRPV2 channels to activation by 2-APB

The cation-permeable TRPV2 channel is important for cardiac and immune cell function. Cannabidiol (CBD), a non-psychoactive cannabinoid of clinical relevance, is one of the few molecules known to activate TRPV2. Using the patch-clamp technique, we discover that CBD can sensitize current responses of...

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Detalles Bibliográficos
Autores principales: Gochman, Aaron, Tan, Xiao-Feng, Bae, Chanhyung, Chen, Helen, Swartz, Kenton J, Jara-Oseguera, Andres
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10195083/
https://www.ncbi.nlm.nih.gov/pubmed/37199723
http://dx.doi.org/10.7554/eLife.86166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10195083/
https://www.ncbi.nlm.nih.gov/pubmed/37199723
http://dx.doi.org/10.7554/eLife.86166

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