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Cannabidiol sensitizes TRPV2 channels to activation by 2-APB
The cation-permeable TRPV2 channel is important for cardiac and immune cell function. Cannabidiol (CBD), a non-psychoactive cannabinoid of clinical relevance, is one of the few molecules known to activate TRPV2. Using the patch-clamp technique, we discover that CBD can sensitize current responses of...
Autores principales: | Gochman, Aaron, Tan, Xiao-Feng, Bae, Chanhyung, Chen, Helen, Swartz, Kenton J, Jara-Oseguera, Andres |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10195083/ https://www.ncbi.nlm.nih.gov/pubmed/37199723 http://dx.doi.org/10.7554/eLife.86166 |
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