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Evaluation of the DBA/2J mouse as a potential background strain for genetic models of cardiomyopathy

The potential use of the D2.mdx mouse (the mdx mutation on the DBA/2J genetic background) as a preclinical model of the cardiac aspects of Duchenne muscular dystrophy (DMD) has been criticized based on speculation that the DBA/2J genetic background displays an inherent hypertrophic cardiomyopathy (H...

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Detalles Bibliográficos
Autores principales: Hart, Cora C., Lee, Young il, Hammers, David W., Sweeney, H. Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10195103/
https://www.ncbi.nlm.nih.gov/pubmed/37206988
http://dx.doi.org/10.1016/j.jmccpl.2022.100012