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IRE1/XBP1 and endoplasmic reticulum signaling — from basic to translational research for cardiovascular disease

Most cellular protein synthesis, including synthesis of membrane-targeted and secreted proteins, which are critical for cellular and organ crosstalk, takes place at the endoplasmic reticulum (ER), placing the ER at the nexus of cellular signaling, growth, metabolism, and stress sensing. Ample eviden...

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Detalles Bibliográficos
Autores principales: Fu, Fangyi, Doroudgar, Shirin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10195104/
https://www.ncbi.nlm.nih.gov/pubmed/37207249
http://dx.doi.org/10.1016/j.cophys.2022.100552