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Developing an Evolutionary Baseline Model for Humans: Jointly Inferring Purifying Selection with Population History

Building evolutionarily appropriate baseline models for natural populations is not only important for answering fundamental questions in population genetics—including quantifying the relative contributions of adaptive versus nonadaptive processes—but also essential for identifying candidate loci exp...

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Detalles Bibliográficos
Autores principales: Johri, Parul, Pfeifer, Susanne P, Jensen, Jeffrey D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10195113/
https://www.ncbi.nlm.nih.gov/pubmed/37128989
http://dx.doi.org/10.1093/molbev/msad100