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Revealing an initiation inhibition of RCA and its application in nucleic acid detection: Initiation inhibition of RCA to detect nucleic acids

Rolling circle amplification is a widely used biosensing technique. Although various secondary structures have been employed in RCA, their effects on RCA efficiency have seldom been reported. Here, we find that stems in circular templates can strongly inhibit RCA, and the primer-stem distance is res...

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Detalles Bibliográficos
Autores principales: Zhuang, Qian, Ge, Meiqiong, Yu, Xiaodong, Chai, Jing, Zhang, Lu, Tang, Suming, Wei, Hua, Zhang, Jinxin, Zhao, Guojie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10195145/
https://www.ncbi.nlm.nih.gov/pubmed/37078748
http://dx.doi.org/10.3724/abbs.2023070