UBE2C promotes leptomeningeal dissemination and is a therapeutic target in brain metastatic disease

BACKGROUND: Despite current improvements in systemic cancer treatment, brain metastases (BM) remain incurable, and there is an unmet clinical need for effective targeted therapies. METHODS: Here, we sought common molecular events in brain metastatic disease. RNA sequencing of thirty human BM identif...

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Detalles Bibliográficos
Autores principales: Paisana, Eunice, Cascão, Rita, Custódia, Carlos, Qin, Nan, Picard, Daniel, Pauck, David, Carvalho, Tânia, Ruivo, Pedro, Barreto, Clara, Doutel, Delfim, Cabeçadas, José, Roque, Rafael, Pimentel, José, Miguéns, José, Remke, Marc, Barata, João T, Faria, Claudia C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Basic and Translational Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10195208/
https://www.ncbi.nlm.nih.gov/pubmed/37215954
http://dx.doi.org/10.1093/noajnl/vdad048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10195208/
https://www.ncbi.nlm.nih.gov/pubmed/37215954
http://dx.doi.org/10.1093/noajnl/vdad048

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