Single cell transcriptomics clarifies the basophil differentiation trajectory and identifies pre-basophils upstream of mature basophils

Basophils are the rarest granulocytes and are recognized as critical cells for type 2 immune responses. However, their differentiation pathway remains to be fully elucidated. Here, we assess the ontogenetic trajectory of basophils by single-cell RNA sequence analysis. Combined with flow cytometric a...

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Detalles Bibliográficos
Autores principales: Miyake, Kensuke, Ito, Junya, Nakabayashi, Jun, Shichino, Shigeyuki, Ishiwata, Kenji, Karasuyama, Hajime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10195816/
https://www.ncbi.nlm.nih.gov/pubmed/37202383
http://dx.doi.org/10.1038/s41467-023-38356-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10195816/
https://www.ncbi.nlm.nih.gov/pubmed/37202383
http://dx.doi.org/10.1038/s41467-023-38356-1

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