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Single cell transcriptomics clarifies the basophil differentiation trajectory and identifies pre-basophils upstream of mature basophils
Basophils are the rarest granulocytes and are recognized as critical cells for type 2 immune responses. However, their differentiation pathway remains to be fully elucidated. Here, we assess the ontogenetic trajectory of basophils by single-cell RNA sequence analysis. Combined with flow cytometric a...
Autores principales: | Miyake, Kensuke, Ito, Junya, Nakabayashi, Jun, Shichino, Shigeyuki, Ishiwata, Kenji, Karasuyama, Hajime |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10195816/ https://www.ncbi.nlm.nih.gov/pubmed/37202383 http://dx.doi.org/10.1038/s41467-023-38356-1 |
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