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Identification of age-specific gene regulators of La Crosse virus neuroinvasion and pathogenesis

One of the key events in viral encephalitis is the ability of virus to enter the central nervous system (CNS). Several encephalitic viruses, including La Crosse Virus (LACV), primarily induce encephalitis in children, but not adults. This phenomenon is also observed in LACV mouse models, where the v...

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Detalles Bibliográficos
Autores principales: Basu, Rahul, Ganesan, Sundar, Winkler, Clayton W., Anzick, Sarah L., Martens, Craig, Peterson, Karin E., Fraser, Iain D. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10195820/
https://www.ncbi.nlm.nih.gov/pubmed/37202395
http://dx.doi.org/10.1038/s41467-023-37833-x