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TIM-3 increases the abundance of type-2 dendritic cells during Leishmania donovani infection by enhancing IL-10 production via STAT3

The outcome of the disease visceral leishmaniasis (VL), caused by Leishmania donovani (LD), largely relies on the relative dominance of host-protective type-1 T helper (Th1) cell response versus disease-promoting type-2 T helper (Th2) cell response. The Th1 and Th2 responses, in turn, are believed t...

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Detalles Bibliográficos
Autores principales: Mishra, Manish, Yadav, Manisha, Kumar, Sandeep, Kumar, Raj, Sen, Pradip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10195822/
https://www.ncbi.nlm.nih.gov/pubmed/37202419
http://dx.doi.org/10.1038/s41419-023-05848-3