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Novel insights into the METTL3-METTL14 complex in musculoskeletal diseases

N6-methyladenosine (m(6)A) modification, catalyzed by methyltransferase complexes (MTCs), plays many roles in multifaceted biological activities. As the most important subunit of MTCs, the METTL3-METTL14 complex is reported to be the initial factor that catalyzes the methylation of adenosines. Recen...

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Detalles Bibliográficos
Autores principales: Xu, Yeqiu, Zhang, Yuanzhuang, Luo, Yinzhou, Qiu, Guanzhen, Lu, Jie, He, Ming, Wang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10195832/
https://www.ncbi.nlm.nih.gov/pubmed/37202385
http://dx.doi.org/10.1038/s41420-023-01435-9