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Identification of RAC1 in promoting brain metastasis of lung adenocarcinoma using single-cell transcriptome sequencing

This study aims to give a new perspective to the biomarkers in the lung adenocarcinoma (LUAD) brain metastasis, pathways involved and potential therapeutics. We performed a comprehensive single-cell level transcriptomic analysis on one LUAD patient with circulating tumor cells (CTCs), primary tumor...

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Detalles Bibliográficos
Autores principales: Chen, Mingyu, Li, Hanyue, Xu, Xiaolin, Bao, Xunxia, Xue, Lei, Ai, Xinghao, Xu, Jian, Xu, Ming, Shi, Yong, Zhen, Timing, Li, Jie, Yang, Yi, Ji, Yang, Fu, Zhiliang, Xing, Kaichen, Qing, Tao, Wang, Qiubo, Zhong, Ping, Zhu, Sibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10195834/
https://www.ncbi.nlm.nih.gov/pubmed/37202394
http://dx.doi.org/10.1038/s41419-023-05823-y