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Enhanced Sestrin expression through Tanshinone 2A treatment improves PI3K-dependent inhibition of glioma growth

Glioblastomas are a highly aggressive cancer type which respond poorly to current pharmaceutical treatments, thus novel therapeutic approaches need to be investigated. One such approach involves the use of the bioactive natural product Tanshinone IIA (T2A) derived from the Chinese herb Danshen, wher...

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Detalles Bibliográficos
Autores principales: Schaf, Judith, Shinhmar, Sonia, Zeng, Qingyu, Pardo, Olivier E., Beesley, Philip, Syed, Nelofer, Williams, Robin S. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10195868/
https://www.ncbi.nlm.nih.gov/pubmed/37202382
http://dx.doi.org/10.1038/s41420-023-01462-6