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Emodin prevents renal ischemia-reperfusion injury via suppression of p53-mediated cell apoptosis based on network pharmacology

BACKGROUND: Previous evidence indicated that emodin has significant advantages for preventing acute kidney injury (AKI). However, the mechanisms responsible for these effects of emodin have yet to be elucidated. METHODS: We first used network pharmacology and molecular docking to identify the core t...

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Detalles Bibliográficos
Autores principales: Lu, Hongmei, Xie, Dengpiao, Qu, Bo, Li, Mingquan, He, Yuhua, Liu, Weijing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10195913/
https://www.ncbi.nlm.nih.gov/pubmed/37215853
http://dx.doi.org/10.1016/j.heliyon.2023.e15682