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Emodin prevents renal ischemia-reperfusion injury via suppression of p53-mediated cell apoptosis based on network pharmacology
BACKGROUND: Previous evidence indicated that emodin has significant advantages for preventing acute kidney injury (AKI). However, the mechanisms responsible for these effects of emodin have yet to be elucidated. METHODS: We first used network pharmacology and molecular docking to identify the core t...
Autores principales: | Lu, Hongmei, Xie, Dengpiao, Qu, Bo, Li, Mingquan, He, Yuhua, Liu, Weijing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10195913/ https://www.ncbi.nlm.nih.gov/pubmed/37215853 http://dx.doi.org/10.1016/j.heliyon.2023.e15682 |
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