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Effect of mTOR Inhibitors in Epilepsy Treatment in Children with Tuberous Sclerosis Complex Under 2 Years of Age

INTRODUCTION: Mechanistic target of rapamycin (mTOR) inhibitors sirolimus and everolimus are an effective therapy for subependymal giant cell astrocytomas, cardiac rhabdomyomas, renal angiomyolipomas, and lymphangioleiomyomatosis associated with tuberous sclerosis complex (TSC). Everolimus was recen...

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Detalles Bibliográficos
Autores principales: Śmiałek, Dominika, Kotulska, Katarzyna, Duda, Aleksandra, Jóźwiak, Sergiusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10195938/
https://www.ncbi.nlm.nih.gov/pubmed/37085686
http://dx.doi.org/10.1007/s40120-023-00476-7