Lipophagy-mediated cholesterol synthesis inhibition is required for the survival of hepatocellular carcinoma under glutamine deprivation

Glutamine is critical for tumor progression, and restriction of its availability is emerging as a potential therapeutic strategy. The metabolic plasticity of tumor cells helps them adapting to glutamine restriction. However, the role of cholesterol metabolism in this process is relatively unexplored...

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Detalles Bibliográficos
Autores principales: Kong, Youzi, Wu, Mengting, Wan, Xiaoyu, Sun, Min, Zhang, Yankun, Wu, Zhuanchang, Li, Chunyang, Liang, Xiaohong, Gao, Lifen, Ma, Chunhong, Yue, Xuetian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10195991/
https://www.ncbi.nlm.nih.gov/pubmed/37150151
http://dx.doi.org/10.1016/j.redox.2023.102732

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10195991/
https://www.ncbi.nlm.nih.gov/pubmed/37150151
http://dx.doi.org/10.1016/j.redox.2023.102732

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