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Metformin inhibits spontaneous excitatory postsynaptic currents in spinal dorsal cord neurons from paclitaxel-treated rats

INTRODUCTION: Cancer patients treated with paclitaxel often develop chemotherapy-induced peripheral neuropathy, which has not been effectively treated with drugs. The anti-diabetic drug metformin is effective in the treatment of neuropathic pain. The aim of this study was to elucidate effect of metf...

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Detalles Bibliográficos
Autores principales: Liu, Ting-Ting, Qiu, Chun-Yu, Hu, Wang-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10195993/
https://www.ncbi.nlm.nih.gov/pubmed/37216004
http://dx.doi.org/10.3389/fnsyn.2023.1191383