A novel mechanism of 6-methoxydihydroavicine in suppressing ovarian carcinoma by disrupting mitochondrial homeostasis and triggering ROS/ MAPK mediated apoptosis

Introduction: Alkaloids derived from M. cordata (Papaveraceae family), have been found to display antineoplastic activity in several types of cancer. However, the antitumor effects and mechanisms of a new alkaloid extracted from the fruits of M. cordata, named 6-Methoxydihydroavicine (6-ME), remains...

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Detalles Bibliográficos
Autores principales: Zhang, Huachang, Shangguan, Fugen, Zhang, Lan, Ma, Nengfang, Song, Shuling, Ma, Li, Liu, Chuntong, Liu, Mengke, An, Jing, Li, Hua, Cao, Qizhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196025/
https://www.ncbi.nlm.nih.gov/pubmed/37214469
http://dx.doi.org/10.3389/fphar.2023.1093650

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196025/
https://www.ncbi.nlm.nih.gov/pubmed/37214469
http://dx.doi.org/10.3389/fphar.2023.1093650

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