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A novel mechanism of 6-methoxydihydroavicine in suppressing ovarian carcinoma by disrupting mitochondrial homeostasis and triggering ROS/ MAPK mediated apoptosis
Introduction: Alkaloids derived from M. cordata (Papaveraceae family), have been found to display antineoplastic activity in several types of cancer. However, the antitumor effects and mechanisms of a new alkaloid extracted from the fruits of M. cordata, named 6-Methoxydihydroavicine (6-ME), remains...
Autores principales: | Zhang, Huachang, Shangguan, Fugen, Zhang, Lan, Ma, Nengfang, Song, Shuling, Ma, Li, Liu, Chuntong, Liu, Mengke, An, Jing, Li, Hua, Cao, Qizhi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196025/ https://www.ncbi.nlm.nih.gov/pubmed/37214469 http://dx.doi.org/10.3389/fphar.2023.1093650 |
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