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Identification and validation of a novel signature based on cell-cell communication in head and neck squamous cell carcinoma by integrated analysis of single-cell transcriptome and bulk RNA-sequencing

BACKGROUND: The heterogeneous crosstalk between tumor cells and other cells in their microenvironment means a notable difference in clinical outcomes of head and neck squamous cell carcinoma (HNSCC). CD8+ T cells and macrophages are effector factors of the immune system, which have direct killing an...

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Detalles Bibliográficos
Autores principales: Wang, Jian, Sun, Hong-Cun, Cao, Cheng, Hu, Jian-Dao, Qian, Jing, Jiang, Tao, Jiang, Wen-Bo, Zhou, Shao, Qiu, Xiao-Wen, Wang, Hong-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196046/
https://www.ncbi.nlm.nih.gov/pubmed/37213285
http://dx.doi.org/10.3389/fonc.2023.1136729