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The assessment of the potential hepatotoxicity of new drugs by in vitro metabolomics

Drug hepatotoxicity assessment is a relevant issue both in the course of drug development as well as in the post marketing phase. The use of human relevant in vitro models in combination with powerful analytical methods (metabolomic analysis) is a promising approach to anticipate, as well as to unde...

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Detalles Bibliográficos
Autores principales: Quintás, Guillermo, Castell, José V., Moreno-Torres, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196061/
https://www.ncbi.nlm.nih.gov/pubmed/37214440
http://dx.doi.org/10.3389/fphar.2023.1155271