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Optogenetic manipulation of cardiac repolarization gradients using sub-threshold illumination

Introduction: Mechanisms underlying cardiac arrhythmias are typically driven by abnormalities in cardiac conduction and/or heterogeneities in repolarization time (RT) across the heart. While conduction slowing can be caused by either electrophysiological defects or physical blockade in cardiac tissu...

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Detalles Bibliográficos
Autores principales: Marchal, Gerard A., Biasci, Valentina, Loew, Leslie M., Biggeri, Annibale, Campione, Marina, Sacconi, Leonardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196067/
https://www.ncbi.nlm.nih.gov/pubmed/37215182
http://dx.doi.org/10.3389/fphys.2023.1167524