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Neuroplastin 65 deficiency reduces amyloid plaque formation and cognitive deficits in an Alzheimer’s disease mouse model

INTRODUCTION: Alzheimer’s disease (AD) is characterized by increasing cognitive dysfunction, progressive cerebral amyloid beta (Aβ) deposition, and neurofibrillary tangle aggregation. However, the molecular mechanisms of AD pathologies have not been completely understood. As synaptic glycoprotein ne...

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Detalles Bibliográficos
Autores principales: Wu, Dan-Dan, Cheng, Jie, Zheng, Ya-Ni, Liu, Yu-Tong, Hou, Shuang-Xin, Liu, Li-Fen, Huang, Liang, Yuan, Qiong-Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196121/
https://www.ncbi.nlm.nih.gov/pubmed/37213217
http://dx.doi.org/10.3389/fncel.2023.1129773