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Mechanisms of action of monoclonal antibodies in oncology integrated in IMGT/mAb-DB

BACKGROUND: Cancer cells activate different immune checkpoint (IC) pathways in order to evade immunosurveillance. Immunotherapies involving ICs either block or stimulate these pathways and enhance the efficiency of the immune system to recognize and attack cancer cells. In this way, the development...

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Detalles Bibliográficos
Autores principales: Manso, Taciana, Kushwaha, Anjana, Abdollahi, Nika, Duroux, Patrice, Giudicelli, Véronique, Kossida, Sofia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196129/
https://www.ncbi.nlm.nih.gov/pubmed/37215135
http://dx.doi.org/10.3389/fimmu.2023.1129323