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Retinal alpha-synuclein accumulation correlates with retinal dysfunction and structural thinning in the A53T mouse model of Parkinson’s disease

Abnormal alpha-synuclein (α-SYN) protein deposition has long been recognized as one of the pathological hallmarks of Parkinson’s disease’s (PD). This study considers the potential utility of PD retinal biomarkers by investigating retinal changes in a well characterized PD model of α-SYN overexpressi...

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Detalles Bibliográficos
Autores principales: Tran, Katie K. N., Wong, Vickie H. Y., Hoang, Anh, Finkelstein, David I., Bui, Bang V., Nguyen, Christine T. O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196133/
https://www.ncbi.nlm.nih.gov/pubmed/37214398
http://dx.doi.org/10.3389/fnins.2023.1146979