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Functional mapping of microRNA promoters with dCas9 fused to transcriptional regulators
MicroRNAs are small non-coding RNAs that control gene expression during development, physiology, and disease. Transcription is a key factor in microRNA abundance and tissue-specific expression. Many databases predict the location of microRNA transcription start sites and promoters. However, these ca...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196145/ https://www.ncbi.nlm.nih.gov/pubmed/37214422 http://dx.doi.org/10.3389/fgene.2023.1147222 |