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Functional mapping of microRNA promoters with dCas9 fused to transcriptional regulators

MicroRNAs are small non-coding RNAs that control gene expression during development, physiology, and disease. Transcription is a key factor in microRNA abundance and tissue-specific expression. Many databases predict the location of microRNA transcription start sites and promoters. However, these ca...

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Detalles Bibliográficos
Autores principales: Kumar, Pradeep, Courtes, Mathilde, Lemmers, Céline, Le Digarcher, Anne, Coku, Ilda, Monteil, Arnaud, Hong, Charles, Varrault, Annie, Liu, Runhua, Wang, Lizhong, Bouschet, Tristan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196145/
https://www.ncbi.nlm.nih.gov/pubmed/37214422
http://dx.doi.org/10.3389/fgene.2023.1147222