RNA demethylase ALKBH5 promotes colorectal cancer progression by posttranscriptional activation of RAB5A in an m6A‐YTHDF2‐dependent manner

BACKGROUND: N6‐methyladenosine (m6A) modification is an emerging epigenetic regulatory mechanism in tumourigenesis. Considering that AlkB homolog 5 (ALKBH5) is a well‐described m6A demethylase in previous enzyme assays, we aimed to investigate the role of m6A methylation alteration conferred by dist...

Descripción completa

Detalles Bibliográficos
Autores principales: Shen, Dingcheng, Lin, Jinxin, Xie, Yumo, Zhuang, Zhuokai, Xu, Gaopo, Peng, Shaoyong, Tang, Guannan, Bai, Liangliang, Zhu, Mingxuan, Zhang, Yu, Huang, Ziying, Wang, Puning, Liu, Xiaoxia, Huang, Meijin, Luo, Yanxin, Wang, Xiaolin, Yu, Huichuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196219/
https://www.ncbi.nlm.nih.gov/pubmed/37203239
http://dx.doi.org/10.1002/ctm2.1279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196219/
https://www.ncbi.nlm.nih.gov/pubmed/37203239
http://dx.doi.org/10.1002/ctm2.1279

Ejemplares similares