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RNA demethylase ALKBH5 promotes colorectal cancer progression by posttranscriptional activation of RAB5A in an m6A‐YTHDF2‐dependent manner

BACKGROUND: N6‐methyladenosine (m6A) modification is an emerging epigenetic regulatory mechanism in tumourigenesis. Considering that AlkB homolog 5 (ALKBH5) is a well‐described m6A demethylase in previous enzyme assays, we aimed to investigate the role of m6A methylation alteration conferred by dist...

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Detalles Bibliográficos
Autores principales:	Shen, Dingcheng, Lin, Jinxin, Xie, Yumo, Zhuang, Zhuokai, Xu, Gaopo, Peng, Shaoyong, Tang, Guannan, Bai, Liangliang, Zhu, Mingxuan, Zhang, Yu, Huang, Ziying, Wang, Puning, Liu, Xiaoxia, Huang, Meijin, Luo, Yanxin, Wang, Xiaolin, Yu, Huichuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196219/ https://www.ncbi.nlm.nih.gov/pubmed/37203239 http://dx.doi.org/10.1002/ctm2.1279

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