Rare variant burden analysis from exomes of three consanguineous families reveals LILRB1 and PRSS3 as potential key proteins in inflammatory bowel disease pathogenesis

BACKGROUND: Inflammatory bowel disease (IBD) is a chronic autoimmune disorder characterized by severe inflammation and mucosal destruction of the intestine. The specific, complex molecular processes underlying IBD pathogenesis are not well understood. Therefore, this study is aimed at identifying an...

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Detalles Bibliográficos
Autores principales: Jan, Rana Mohammed, Al-Numan, Huda Husain, Al-Twaty, Nada Hassan, Alrayes, Nuha, Alsufyani, Hadeel A., Alaifan, Meshari A., Alhussaini, Bakr H., Shaik, Noor Ahmad, Awan, Zuhier, Qari, Yousef, Saadah, Omar I., Banaganapalli, Babajan, Mosli, Mahmoud Hisham, Elango, Ramu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196255/
https://www.ncbi.nlm.nih.gov/pubmed/37215724
http://dx.doi.org/10.3389/fmed.2023.1164305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196255/
https://www.ncbi.nlm.nih.gov/pubmed/37215724
http://dx.doi.org/10.3389/fmed.2023.1164305

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