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Detoxified synthetic bacterial membrane vesicles as a vaccine platform against bacteria and SARS-CoV-2

The development of vaccines based on outer membrane vesicles (OMV) that naturally bud off from bacteria is an evolving field in infectious diseases. However, the inherent inflammatory nature of OMV limits their use as human vaccines. This study employed an engineered vesicle technology to develop sy...

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Detalles Bibliográficos
Autores principales: Park, Kyong-Su, Svennerholm, Kristina, Crescitelli, Rossella, Lässer, Cecilia, Gribonika, Inta, Andersson, Mickael, Boström, Jonas, Alalam, Hanna, Harandi, Ali M, Farewell, Anne, Lötvall, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196325/
https://www.ncbi.nlm.nih.gov/pubmed/37208676
http://dx.doi.org/10.1186/s12951-023-01928-w