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Detoxified synthetic bacterial membrane vesicles as a vaccine platform against bacteria and SARS-CoV-2
The development of vaccines based on outer membrane vesicles (OMV) that naturally bud off from bacteria is an evolving field in infectious diseases. However, the inherent inflammatory nature of OMV limits their use as human vaccines. This study employed an engineered vesicle technology to develop sy...
Autores principales: | Park, Kyong-Su, Svennerholm, Kristina, Crescitelli, Rossella, Lässer, Cecilia, Gribonika, Inta, Andersson, Mickael, Boström, Jonas, Alalam, Hanna, Harandi, Ali M, Farewell, Anne, Lötvall, Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196325/ https://www.ncbi.nlm.nih.gov/pubmed/37208676 http://dx.doi.org/10.1186/s12951-023-01928-w |
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