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Relationship between factor VIII levels and bleeding for rFVIII‐SingleChain in severe hemophilia A: A repeated time‐to‐event analysis

Publications on the exposure‐effect relationships of factor concentrates for hemophilia treatment are limited, whereas such analyses give insight on treatment efficacy. Our objective was to examine the relationship between the dose, factor VIII (FVIII) levels and bleeding for rFVIII‐SingleChain (lon...

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Detalles Bibliográficos
Autores principales: Bukkems, Laura H., Jönsson, Siv, Cnossen, Marjon H., Karlsson, Mats O., Mathôt, Ron A. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196421/
https://www.ncbi.nlm.nih.gov/pubmed/36965157
http://dx.doi.org/10.1002/psp4.12938