Genome mining for anti-CRISPR operons using machine learning

MOTIVATION: Encoded by (pro-)viruses, anti-CRISPR (Acr) proteins inhibit the CRISPR-Cas immune system of their prokaryotic hosts. As a result, Acr proteins can be employed to develop more controllable CRISPR-Cas genome editing tools. Recent studies revealed that known acr genes often coexist with ot...

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Detalles Bibliográficos
Autores principales: Yang, Bowen, Khatri, Minal, Zheng, Jinfang, Deogun, Jitender, Yin, Yanbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Applications Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196667/
https://www.ncbi.nlm.nih.gov/pubmed/37158576
http://dx.doi.org/10.1093/bioinformatics/btad309

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196667/
https://www.ncbi.nlm.nih.gov/pubmed/37158576
http://dx.doi.org/10.1093/bioinformatics/btad309

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