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Accelerated epigenetic aging and DNA methylation alterations in Berardinelli–Seip congenital lipodystrophy

Berardinelli–Seip congenital lipodystrophy type 2 (CGL2) is a very rare human genetic disorder with potential significance to the understanding of the pathobiology of aging. CGL2 patients display characteristic progeroid features and suffer from type 2 diabetes, insulin resistance and fatty liver. I...

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Detalles Bibliográficos
Autores principales: Qannan, Abeer, Bejaoui, Yosra, Izadi, Mahmoud, Yousri, Noha A, Razzaq, Aleem, Christiansen, Colette, Martin, George M, Bell, Jordana T, Horvath, Steve, Oshima, Junko, Megarbane, Andre, Ericsson, Johan, Pourkarimi, Ehsan, El Hajj, Nady
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196674/
https://www.ncbi.nlm.nih.gov/pubmed/36715159
http://dx.doi.org/10.1093/hmg/ddad016