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Assessing the effects of aging on the renal endothelial cell landscape using single-cell RNA sequencing

Endothelial cells (ECs) with senescence-associated secretory phenotypes (SASP) have been identified as a key mechanism of aging that contributes to various age-related kidney diseases. In this study, we used single-cell RNA sequencing (scRNA-seq) to create a transcriptome atlas of murine renal ECs a...

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Detalles Bibliográficos
Autores principales: Li, Mengke, Wang, Dongliang, Liu, Zhong, Huang, Yanjing, Zhang, Qikai, Pan, Caineng, Lin, Yuheng, Sun, Li, Zheng, Yingfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196692/
https://www.ncbi.nlm.nih.gov/pubmed/37214419
http://dx.doi.org/10.3389/fgene.2023.1175716