Combination of PARP and WEE1 inhibitors in vitro: Potential for use in the treatment of SHH medulloblastoma

Medulloblastoma (MB), grouped as either WNT-activated, Sonic hedgehog (SHH)-activated, or non-WNT/non-SHH group 3, accounts for almost 20% of all childhood brain cancers. In spite of current intensive treatments, not all patients are cured and survivors suffer from severe side-effects. The present s...

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Detalles Bibliográficos
Autores principales: Lukoseviciute, Monika, Theodosopoulou, Aikaterini, Holzhauser, Stefan, Dalianis, Tina, Kostopoulou, Ourania N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196712/
https://www.ncbi.nlm.nih.gov/pubmed/37144508
http://dx.doi.org/10.3892/or.2023.8562

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196712/
https://www.ncbi.nlm.nih.gov/pubmed/37144508
http://dx.doi.org/10.3892/or.2023.8562

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