Cargando…

Alpha-adrenergic receptor activation after fetal hypoxia-ischaemia suppresses transient epileptiform activity and limits loss of oligodendrocytes and hippocampal neurons

Exposure to hypoxic-ischaemia (HI) is consistently followed by a delayed fall in cerebral perfusion. In preterm fetal sheep this is associated with impaired cerebral oxygenation, consistent with mismatch between perfusion and metabolism. In the present study we tested the hypothesis that alpha-adren...

Descripción completa

Detalles Bibliográficos
Autores principales: Dhillon, Simerdeep K, Gunn, Eleanor R, Pedersen, Mette V, Lear, Christopher A, Wassink, Guido, Davidson, Joanne O, Gunn, Alistair J, Bennet, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196751/
https://www.ncbi.nlm.nih.gov/pubmed/36703575
http://dx.doi.org/10.1177/0271678X231153723