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Alpha-adrenergic receptor activation after fetal hypoxia-ischaemia suppresses transient epileptiform activity and limits loss of oligodendrocytes and hippocampal neurons
Exposure to hypoxic-ischaemia (HI) is consistently followed by a delayed fall in cerebral perfusion. In preterm fetal sheep this is associated with impaired cerebral oxygenation, consistent with mismatch between perfusion and metabolism. In the present study we tested the hypothesis that alpha-adren...
Autores principales: | Dhillon, Simerdeep K, Gunn, Eleanor R, Pedersen, Mette V, Lear, Christopher A, Wassink, Guido, Davidson, Joanne O, Gunn, Alistair J, Bennet, Laura |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196751/ https://www.ncbi.nlm.nih.gov/pubmed/36703575 http://dx.doi.org/10.1177/0271678X231153723 |
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