Membrane bending and sphingomyelinase-associated, sulfatide-dependent hypoxic adhesion of sickle mature erythrocytes

Abnormal erythrocyte adhesion owing to polymerization of sickle hemoglobin is central to the pathophysiology of sickle cell disease (SCD). Mature erythrocytes constitute >80% of all erythrocytes in SCD; however, the relative contributions of erythrocytes to acute and chronic vasculopathy in SCD a...

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Detalles Bibliográficos
Autores principales: Goreke, Utku, Kucukal, Erdem, Wang, Fang, An, Ran, Arnold, Nicole, Quinn, Erina, Yuan, Charlotte, Bode, Allison, Hill, Ailis, Man, Yuncheng, Hambley, Bryan C., Schilz, Robert, Ginwalla, Mahazarin, Little, Jane A., Gurkan, Umut A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Red Cells, Iron, and Erythropoiesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196783/
https://www.ncbi.nlm.nih.gov/pubmed/36652689
http://dx.doi.org/10.1182/bloodadvances.2022008392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196783/
https://www.ncbi.nlm.nih.gov/pubmed/36652689
http://dx.doi.org/10.1182/bloodadvances.2022008392

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